DHEA supplements seem to be everywhere these days, so I wanted to take a moment to dive into what makes this hormone so important. I frequently test for DHEA when assessing adrenal and sex hormones (like estrogen, progesterone, and testosterone), but it doesn’t get the attention it deserves in most health conversations. Let’s change that!
What is DHEA?
DHEA, short for dehydroepiandrosterone, is a hormone primarily produced by your adrenal glands—those tiny, pyramid-shaped glands that sit on top of your kidneys. These glands are responsible for producing many essential hormones.
Your body starts ramping up DHEA production between ages 6 and 8, a stage called adrenarche, to prepare for the hormonal shifts of puberty. DHEA levels peak in your twenties and gradually decline with age.
Men generally have higher DHEA levels than women, but both experience a steady drop as they get older.
What does DHEA do?
As the most abundant hormone in the body, DHEA is a big deal. It acts as a building block for other hormones, including testosterone and estrogen. Beyond that, it plays a role in managing stress by working with cortisol, the body’s primary stress hormone.
Studies suggest DHEA can improve mood, boost alertness, and help you handle stress more effectively. But that’s not all—it also supports immune function, muscle growth, libido, brain health, memory, and tissue repair. Research has even looked into its potential benefits for bone health, particularly for postmenopausal women, as it may help increase bone density in key areas like the spine and hips.
How do you test for DHEA?
When I test DHEA levels, I often use saliva tests as part of an adrenal hormone profile. I may also measure DHEA-S, the inactive storage form, which can be tested through saliva or blood. Understanding the difference between the active and inactive forms is crucial for interpreting results and determining the best course of action.
Should you supplement with DHEA?
While DHEA supplements may sound like a miracle solution, they aren’t without risks. Since DHEA converts into other hormones, taking it can sometimes lead to unwanted side effects like acne or hair loss. It’s also not recommended for individuals with hormone-sensitive conditions, like certain cancers. This is why DHEA supplementation should only be done under the supervision of a healthcare professional who can evaluate your unique hormonal needs.
When I consider DHEA supplementation, I always look at adrenal health, liver function, and overall hormone balance first. But honestly, supplementation is rarely my go-to. Instead, I focus on lifestyle changes and natural supports to encourage the body’s own DHEA production. Chronic stress is a major culprit behind low DHEA levels, so managing stress is key. Mindfulness practices, regular exercise, quality sleep, and a diet rich in healthy fats (and low in sugar) can make a huge difference. I also use herbal adaptogens and specific nutraceuticals to support hormone health naturally.
The bigger picture
DHEA is a great example of how interconnected the endocrine system is. Hormones don’t act in isolation—they work together like a well-tuned orchestra. Factors like gut health, liver function, and chronic inflammation can all affect DHEA levels. For instance, poor gut health can disrupt hormone metabolism, while the liver plays a crucial role in regulating hormones, including DHEA.
As we age, keeping our hormones balanced becomes even more important. Taking a holistic approach—focusing on stress management, proper nutrition, and overall well-being—can address the root causes of low DHEA and help you feel energized and resilient. By supporting your body naturally, you’re setting the stage for better energy, mood, and long-term health.
Contact our office to schedule an appointment or a complimentary consultation with one of our naturopathic doctors. We’re here to help!
Follow us on Instagram to learn more from our team.
Dr. Jennifer Potter, ND
Naturopathic Doctor San Jose
408-356-1364
