Thyroid Hormones and Menopause

Thyroid Hormones and Menopause

Menopause marks a natural shift in a woman’s life.

While most women expect menstrual cycles to cease at some point in time, many are unaware of the array of changes and health effects that come with it. Thyroid changes during menopause are common and need extra care during this phase. 

Most commonly thyroid function decreases during this time, adding to peri-menopausal fatigue, brain fog, emotional changes, weight gain and more.  

Thyroid Hormone Basics

The thyroid gland produces hormones that play a vital role in regulating metabolism, energy levels, and the function of many systems in the body.

Thyroid hormones, mainly triiodothyronine (T3) and thyroxine (T4), influence the way your body uses energy, thus impacting nearly every organ – leading to their nickname, the metabolic juggernauts.

Thyroid Hormones and Menopause

During menopause, the levels of estrogen and progesterone, the sex hormones, fluctuate and gradually decrease. These hormonal shifts can indirectly influence thyroid function as sex hormones play a role in thyroid hormone metabolism. Furthermore, estrogen has been found to affect your cells’ sensitivity to thyroid hormone.

Your thyroid hormones and adrenal system are closely connected.

The adrenals help in regulating metabolism, stress response, the immune system, and blood pressure. Fluctuations in your sex hormones and thyroid hormones can increase stress on your body, potentially straining the adrenal system and leading to adrenal dysfunction. This, in turn, affects thyroid function, creating a cycle of dysfunction that may result in symptoms like fatigue, anxiety and depression.

Weight gain is another common concern during menopause, and a less than optimal thyroid function can exacerbate this problem. Thyroid hormones play a crucial role in regulating metabolism, and even a slight imbalance may slow metabolic rate, making weight management more challenging.

After menopause, the likelihood of thyroid disorders rises.

Managing this requires care as thyroid hormone replacement might impact heart health and bone strength if not applied correctly.


The symptoms of thyroid dysfunction can be similar to menopausal symptoms, making diagnosis and effective treatment tricky. Additionally, the interpretation of thyroid function tests requires a nuanced approach during menopause, as physiological changes could alter thyroid hormones’ secretion and metabolism.

Optimizing thyroid function during menopause is not merely about balancing hormones for the sake of routine health maintenance; it’s about ensuring overall wellbeing as the body navigates through a significant hormonal transition.

Monitoring and, if necessary, adjusting thyroid hormone levels through appropriate interventions like lifestyle changes, nutrition, exercise, and when indicated, medical therapies including thyroid hormone and sex hormone replacement therapy, can greatly enhance quality of life during menopause and beyond.

If you’re approaching menopause, work closely with your healthcare providers to monitor thyroid function as part of your comprehensive health plan.

Early detection and treatment of thyroid dysfunction can mitigate risks and improve outcomes during these challenging times.  Being proactive about thyroid health can lead to better management of menopause symptoms, improved metabolic health, and overall longevity. 

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Dr. Sadi Jimenez, ND San Jose

Dr. Sadi Jimenez
Naturopathic Doctor San Jose


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